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Exp Clin Endocrinol Diabetes 1995; 103(4): 272-274
DOI: 10.1055/s-0029-1211362
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Effect of FSH on progesterone secretion by porcine large and small luteal cells isolated from early-developing corpora lutea

E. L. Gregoraszczuk
  • Laboratory of Animal Endocrinology and Tissue Culture, Department of Animal Physiology, Institute of Zoology, Jagiellonian University, Kraków, Poland
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Publication Date:
15 July 2009 (online)

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Summary

Isolated porcine luteal cells from d 0—3 of the estrous cycle (estrus — d 0) were incubated with or without addition of 0, 10, 102 or 103 ng FSH/ml. Progesterone (P4) content was determinated after 24 hrs of incubation.

In nonstimulated conditions the basal P4 production of large cells (LCs) was 65 fold higher than that of small cells (SCs). The LCs but not SCs were stimulated by doses of 10 and 102 ng FSH. FSH in doses of 10 and 102 ng did not influence P4 production by SCS, but higher doses (103 ng) significantly decreased their P4 secretion.

The results indicated that FSH can have a distinct cellular luteotropic effect during the early development luteal phase of the pig. FSH influenced P4 secretion by LCS whereas, with SCs it had no effect (10 and 102 ng) or P4 secretion decreased (103 ng).

Key words

FSH - corpus luteum - pigs - progesterone secretion

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