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Exp Clin Endocrinol Diabetes 1993; 101(3): 156-160
DOI: 10.1055/s-0029-1211223
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Aspartate-Aminopeptidase Activity during the Estrous Cycle and the Pregnancy in Rat Brain and Pituitary Gland

J. M. de Gandarias, J. Irazusta, E. Echevarria, L. Casis
  • Department of Physiology, Medical School, University of the Basque Country, Bilbao/Spain
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Publication History

Publication Date:
15 July 2009 (online)

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Summary

The present report describes the activity of aspartate aminopeptidase, in 9 brain areas and in the pituitary gland, during the estrous cycle and several stages of pregnancy of the rat. The quantitation of the enzyme activity was performed by measuring the rate of hydrolysis of the chromogenic substrate Asp-β-naphthylamide. Aspartate aminopeptidase activity, in the pituitary gland and in several limbic areas, was found to be greater in cyclic than in pregnant rats. However the enzyme activity did not change significantly during either the estrous cycle and pregnancy.

Key words

Asp-Aminopeptidase activity - Pregnancy - Estrous Cycle - Rat Brain