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Exp Clin Endocrinol Diabetes 1989; 94(4/05): 89-96
DOI: 10.1055/s-0029-1210884
Original

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Effect of Endurance Exercise on Somatomedin- C/lnsulin-like Growth Factor I Concentration in Male and Female Runners*)

G. Jahreis1 , V. Hesse1 , H. E. Schmidt2 , J. Scheibe3
  • 1Children's Hospital (Director: Prof. Dr. G. Zwacka) of the Friedrich-Schiller-University, Division of Paediatric Endocrinology (Head: Prof. Dr. V. Hesse), Central Institute for Isotope and Radiation Research, Jena, GDR
  • 2Department of Radiation Sources and Radiopharmaceuticals, GDR Academy of Sciences, Berlin-Buch (Head: Prof. Dr. G. Vormum), Jena, GDR
  • 3Chair of Sports (Head: Prof. Dr. J. Scheibe) of the Friedrich-Schiller-University, Jena, GDR
*) Dedicated to Professor Dr. G. Dörner on the occasion of his 60th birthday.
Further Information

Publication History

1988

Publication Date:
16 July 2009 (online)

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Summary

By means of 3 endurance exercises, the effect of a several-hour intensive somatic stress on the changes of the Sm-C/IGF-I concentration was tested during, immediately after and on the day following the exercise. Exp. 1: Marathon with 17 male sportsmen in 2 groups with different glucose supply. Exp. 2: 45-km crosscountry run with 41 males. Exp. 3: Three 20-km runs with 8 young females at intervals of 3 months. In the marathon, no significant changes of the Sm-C/IGF-I concentration were found between the start, half distance and final values. The exogenous glucose supply (continuous or discontinuous) had also no effect. The tendency of a slight decrease of the Sm-C/IGF-I concentration by 0.14 U/ml (p > 0.05) was observed between start and finish in the 45 km crosscountry run lasting one hour longer. In the three 20-km runs, reproducible, slightly increased levels were measured at the end, whereas a decrease to the initial value or even below was detected on the following day (p > 0.05). The insignificant alterations of the Sm-C/IGF-I concentration measured in the 3 variants of races show that neither the hormonal changes stimulating the Sm-C/IGF-I synthesis (e.g. increase of GH and prolactin) nor inhibiting factors (energy deficiency) clearly dominate during strenuous exercises. The binding of carrier protein prevents great variations of the Sm-C/IGF-I level even under the condition of 3- to 4-hour extreme endurance exercises.

Key words

Endurance run - Somatomedin-C/insulin-like growth factor I - Growth hormone

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