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Exp Clin Endocrinol Diabetes 1988; 91(2): 235-237
DOI: 10.1055/s-0029-1210752
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Influence of Electrical Stimulation of the Limbic Structure on Ovarian Steroidogenesis in Hypophysectomized and Adrenalectomized Rats

K. Seto, H. Saito, H. Kaba, A. Honmura, Cheng-Shu Li, M. Nakagawa1 , H. Ikeda1 , M. Kawakami2
  • First Department of Physiology (Chairman: Prof. Dr. K. Seto), Kochi Medical School, Nankoku/Japan
  • 1Department of Neuropsychiatry (Chairman: Prof. Dr. H. Ikeda), Kochi Medical School, Nankoku/Japan
  • 2Second Department of Physiology (Former Chairman: Prof. Dr. M. Kawakami) Yokohama City University School of Medicine, Yokohama/Japan
Further Information

Publication History

1987

Publication Date:
16 July 2009 (online)

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Summary

The effects of electrical stimulation of the medial amygdala (AMYG) and dorsal hippocampus (DHPC) on the rates of 14C transfer from 14C-1-acetate into ovarian steroids in hypophysectomized and adrenalectomized rats (H-A rats) were investigated. The 14C transfer rates into estrogen were increased by stimulation of AMYG and DHPC. The 14C transfer rates into progesterone and 20α-hydroxy-pregn-4-en-3-one (20α-OH-P) were increased by the AMYG stimulation but decreased by the DHPC stimulation.

From these results, it might be suggested that these limbic structures were involved in the regulation of ovarian steroidogenesis without participation of pituitary and adrenal.

Key words

Limbic Structure - Ovarian Steroids - Hypophysectomized rats

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