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Exp Clin Endocrinol Diabetes 1987; 89(1): 16-22
DOI: 10.1055/s-0029-1210622
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Changes in Mouse Leydig Cell Steroidogenesis Following Infrared and Helium-Neon Laser Irradiation

M. F. Celani, M. Grandi, G. Gilioli
  • Department of Endocrinology (Director: Prof. P. Marrama) and Department of Internal Medicine (Director: Prof. B. Bonati), Faculty of Medicine, University of Modena/Italy
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Publication History

1986

Publication Date:
16 July 2009 (online)

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Summary

The effects on mouse Leydig cell steroidogenesis of infrared (IR) laser rays, in the presence or absence of helium-neon (He-Ne) radiations, were investigated. Testosterone (T) production in response to luteinizing hormone (LH) by mouse Leydig cells exposed to IR (4.2 × 10−3 J/cm2/ min) plus He-Ne (8.0 × 10−7 J/cm2/min) laser radiations was significantly higher than that by control Leydig cells. The Leydig cell responsiveness to LH (TΔ%), as well as the secretion of cyclic AMP (cAMP) and androstenedione (A) in response to the highest dose of LH (0.5 mIU), were also significantly increased by the IR plus He-Ne irradiation. In contrast, the He-Ne irradiation (8.0 × 10−7 J/cm2/min) in the absence of IR rays failed to affect T production by mouse Leydig cells. Similar results were obtained by adding to the He-Ne rays a low dose of IR radiation (3.4 × 10−3 J/cm2/min), whereas higher doses of IR radiations (4.2 × l0−3 and 5.1 × l0−3 J/cm2/min) elicited a similar significant increase of T production by mouse interstitial cells.

Key words

Infrared laser radiations - Helium-neon laser radiations - Mouse Leydig cell steroidogenesis