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Exp Clin Endocrinol Diabetes 1986; 87(3): 349-352
DOI: 10.1055/s-0029-1210567
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Effect of Antiandrogens on the Hypothalamic Gamma-Aminobutyric Acid (GABA) and Glutamate Contents of the Indian Palm Squirrel (Funambulus pennanti, Wroughton)

Vinoy K. Shrivastava, A. G. Sathyanesan
  • Reproductive Physiology Laboratory, Department of Zoology, Banaras Hindu University, Varanasi/India
Further Information

Publication History

1985

Publication Date:
16 July 2009 (online)

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Summary

Intramuscular administration of 20 mg/kg flutamide (Flut) or 50 mg/kg of cyproterone acetate (CPA) daily for a period of three weeks significantly elevated the hypothalamic GABA content. CPA is found to decrease the hypothalamic glutamate level while Flut elevated it. Both, Flut and CPA reduced the hypothalamic weight.

Key words

Hypothalamus - GABA - Glutamate - Antiandrogens

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