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Exp Clin Endocrinol Diabetes 1985; 85(3): 257-262
DOI: 10.1055/s-0029-1210447
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

The Influence of a Sequential-Type Oral Contraceptive with Ethinylestradiol-Sulfonate Soft Gelatin Capsules and Norethisterone Acetate on Carbohydrate Metabolism during the First Twelve Months *)

S. Nikschick, G. Göretzlehner, E. Männchen1 , K. Brachmann2
  • Department of Obstetrics and Gynecology (Head: MR Prof. Dr. sc. med. G. Göretzlehner)
  • 1Department of Medicine, (Head: Prof. Dr. sc. med. B. Wedler) Ernst-Moritz-Arndt-University of Greifswald/GDR
  • 2Department of Central Laboratory (Head: Prof. Dr. sc. med. W. Haude), Ernst-Moritz-Arndt-University of Greifswald/GDR
*) In co-operation with VEB Jenaphram, Jena/GDR.
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Publikationsverlauf

1984

Publikationsdatum:
16. Juli 2009 (online)

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Summary

A prospective study was made to investigate the carbohydrate metabolic effects of the sequential-type oral contraceptive in form of a weekly pill with 0.6 mg ethinylestradiolsulfonate soft gelatin capsules and 10 mg norethisterone acetate. Blood glucose and plasma insulin levels were measured during an intravenous glucose tolerance test in 17 nondiabetic healthy women. Each woman was tested before and after twelve months of drug use. There were no changes neither in average fasting blood glucose nor in glucose assimilation after intake of ethinylestradiol-sulfonate. At twelve months there were significant elevations of basal as well as reactive insulin levels.

Key words

Hormonal contraceptives - “Weekly pill” - Glucose - Insulin