The Effect of Five Days Calcium Chloride Treatment on the Somatostatin Cells of the Antral Mucosa in White Rats1)

Mileva Ivić; Lj. Klisić; Vuka Katić

doi:10.1055/s-0029-1210352

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Exp Clin Endocrinol Diabetes 1984; 83(3): 349-352
DOI: 10.1055/s-0029-1210352

Original

The Effect of Five Days Calcium Chloride Treatment on the Somatostatin Cells of the Antral Mucosa in White Rats¹)

Mileva Ivić, Lj. Klisić, Vuka Katić

Institute of Physiology and Institute of Pathology, Faculty of Medicine, Niš/Yugoslavia

1) This work was supported by a grant from RZN of Serbia.

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Publikationsverlauf

1982

Publikationsdatum:
17. Juli 2009 (online)

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Summary

The effects of a five day treatment with calcium chloride (1 ml 0.11 M CaCl₂/100g body weight i.p., twice daily) on somatostatin cells in gastric antral mucosa of white rats were investigated. Somatostatin cells of experimental and control animals were identified by immunoperoxidase method using rabbit antihuman antisomatostatin (1:1000), and counted on perpendicularly cut sections taken from four transversal levels going from pylorus to antrofundic border.

The results obtained have demonstrated the occurrence of somatostatin cell hyperplasia in animals treated with calcium chloride, established on the ground of highly significant rise in the number of somatostatin cells and a change in their topography.

Key words

Gastric somatostatin cells - mouse - calcium chloride