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Exp Clin Endocrinol Diabetes 1983; 82(6): 376-379
DOI: 10.1055/s-0029-1210302
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Ultrastructural Changes in the Neural Lobe of the Rat Pituitary Following Nicotine Pretreatment

S. C. Maitra, K. Chakraverty1) , A. C. Shipstone, K. Kar
  • E. M. Unit and Department of Pharmacology (Director: Nityanand) Central Drug Research Institute, Lucknow/India
1) Recipient of Research Fellowship award from Indian Council of Medical Research.
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Publikationsverlauf

1982

Publikationsdatum:
17. Juli 2009 (online)

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Summary

The effect of nicotine on the ultrastructural changes and hormone contents of the neural lobe of the pituitary were studied in the rat. Nicotine caused a significant release of both vasopressin and oxytocin from the neural lobe. The eximanation of the neural lobe with electron microscope reveals the nerve terminals depleted of neurosecretory granules. These results suggest that a definite correlation exists between hormone contents and ultrastructural morphology.