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Exp Clin Endocrinol Diabetes 1983; 82(6): 337-341
DOI: 10.1055/s-0029-1210295
Original

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Fertility Control in Vas Occluded Rats and the Biochemical Effects of Ascorbic Acid Feeding

J. D. Sharma, N. J. Chinoy1 , V. P. Dixit
  • 1Reproduction Physiology Section, Department of Zoology, University of Rajasthan, Jaipur and Zoology Department, School of Sciences, Gujarat University, Ahmedabad
  • Reproduction Physiology Section, Department of Zoology, University of Rajasthan, Jaipur and Zoology Department, School of Sciences, Gujarat University, India.
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1982

Publikationsdatum:
17. Juli 2009 (online)

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Summary

A new approach to rapid male sterilization has been studied by giving a single injection of 95% ethanol directly into the vas deferens. It produced an effective block in the lumen. The mating exposure test showed that the males were sterile. Vas occlusion caused an atrophy of the Cauda epididymis. Extensive necrosis arid exfoliation of the seminiferous elements were conspicuous.

Reduced succiriate dehydrogenase, acid phosphatase, vesicular fructose and altered ascorbate turnover pattern could be restored to normal by simultaneous ascorbic acid feeding. In conclusion ascorbic acid feeding plays a definite beneficial role in vas occluded rats. The antiandrogenic effects of vas occlusion could be reversed by simultaneous ascorbic acid feeding.