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DOI: 10.1055/s-0029-1185449
© Georg Thieme Verlag KG Stuttgart · New York
15-Lipoxygenase Inhibitory Effects of Prenylated Flavonoids from Erythrina senegalensis
Publication History
received December 17, 2008
revised January 28, 2009
accepted February 3, 2009
Publication Date:
13 March 2009 (online)
Abstract
One new pterocarpan (named erybraedin F) along with seven known prenylated flavonoids were isolated from the stem and root bark of the medicinal plant Erythrina senegalensis. The structures were elucidated by 1D and 2D NMR and MS. The pterocarpans were found to be strong inhibitors of 15-lipoxygenase.
Key words
Erythrina senegalensis (Fabaceae) - pterocarpans - flavonoid - DPPH - 15‐lipoxygenase
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Karl Egil Malterud
Department of Pharmaceutical Chemistry
Division of Pharmacognosy
School of Pharmacy
University of Oslo
P. O. Box 1068
0316 Oslo
Norway
Phone: + 47 22 85 65 63
Email: k.e.malterud@farmasi.uio.no