STOFFWECHSEL UND ABBAU VON PHENYLÄTHYLAMINEN IN PFLANZLICHEN ZELLSUSPENSIONSKULTUREN

Abstract

To investigate the catabolic pathways of phenylethylamine alcaloids in plant cell suspension cultures preliminary experiments with (2– ¹⁴ C)–tyramine and (2– ¹⁴ C)–dopamine were performed. In numerous cell suspension cultures formation of ¹⁴ CO₂ from both substrates ranging from 0,5–1,2 % (tyramine) to 0,8–2,7 % (dopamine) could be observed. As main metabolites of tyramine p–hydroxyphenylacetic acid and p–hydroxybenzoic acid could be identified whereas evidence for the formation of 3,4–dihydroxyphenylacetic acid from tyramine could also be obtained.