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Planta Med 1964; 12(2): 149-154
DOI: 10.1055/s-0028-1100160
© Georg Thieme Verlag Stuttgart · New York

INVESTIGATIONS OF CERTAIN NIGERIAN MEDICINAL PLANTS – Part. II. Some observations on the alkaloid content of Pleiocarpa pycnantha (K. Schum.) Stapf var. tubicina (Stapf) Pichon.

M. B. Patel1 , J. M. Rowson
  • From the Department of Pharmacy, Nigerian College of Technology, Ibadan; and the Department of Pharmacy, Institute of Technology, Bradford.
1 This paper represents part of the work submitted by one of the authors (M. B. P.) for the degree of Doctor of Philosophy of the University of London.
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Publication History

Publication Date:
15 January 2009 (online)

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See also:

INVESTIGATIONS OF CERTAIN NIGERIAN MEDICINAL PLANTS – Part III. The Anatomy of the Leaf of Pleiocarpa pycnantha (K. Schum.) Stapf var. tubicina (Stapf) PichonPlanta Med 1964; 12(02): 194-204
DOI: 10.1055/s-0028-1100169

See also:

INVESTIGATIONS OF CERTAIN NIGERIAN MEDICINAL PLANTS – Part. I. Preliminary Pharmacological and Phytochemical Screenings for Cardiac Activity1Planta Med 1964; 12(01): 33-42
DOI: 10.1055/s-0028-1100147

Summary

The dried seed kernels, root bark and leaves of Pleiocarpa pycnantha var. tubicina have been shown to contain large amounts of both strong and weak tertiary alkaloids. Stem bark or wood and root wood contained much smaller quantities of these alkaloids. Pleiocarpine was the principal weak tertiary alkaloid in each of the morphological members examined except the leaf, which was free from this base. A new weak tertiary base tubicinine chloride (C21H28N2O5Cl2, m. p. 212°–214° with decomposition) was found in the leaf only, in amounts of 0.1 per cent.

Zusammenfassung

Samenkerne, Wurzelrinde und Blätter von Pleiocarpa pycnantha var. tubicina enthalten große Mengen starker und schwacher tertiärer Alkaloide, während das Holz von Wurzel und Stamm wie auch die Stammrinde nur geringe Mengen dieser Alkaloide enthalten. Mit Ausnahme der Blätter ist in allen genannten Geweben das Pleiocarpin das Hauptalkaloid. Nur in den Blättern vorkommend wurde als neue schwache tertiäre Base Tubicininchlorid gefunden.

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