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Horm Metab Res 1970; 2(1): 32-34
DOI: 10.1055/s-0028-1095124
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© Georg Thieme Verlag KG Stuttgart · New York

Retention of 47 Calcium Administered Orally in Patients with Primary Hyperparathyroidism[*]

H. E. Sjöberg [**]
  • The Department of Endocrinology and Metabolism, and the Department of Internal Medicine, Karolinska Hospital, Stockholm, Sweden
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Publication History

Publication Date:
08 January 2009 (online)

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Abstract

Calcium retention in a group of nine patients with primary hyperparathyroidism was measured in a whole body counter one and two weeks after administration of a single oral dose of 47 Ca with 135 mg Ca++. The mean retention value was higher than in healthy controls. The loss of 47 Ca into the urine was also increased. These findings are interpreted as demonstrating a substantially increased calcium absorption from the intestine and is attributed to increased production of parathyroid hormone. Furthermore, increased intestinal absorption is suggested to contribute to the increased plasma calcium level in primary hyperparathyroidism.

Key words

Primary Hyperparathyroidism Calcium Absorption - Calcium Retention - 47 Calcium - Whole Body Counter

1 This work was supported by grants-in-aid from the Loo and Hans Osterman's Foundation.

1 This work was supported by grants-in-aid from the Loo and Hans Osterman's Foundation.

2