Abstract
The aim of the present study was to investigate the existence of a transferable "exercise
factor" which facilitates glucose transport. Rat hemidiaphragms were incubated either
in rat plasma obtained from fasted donors or in rat plasma which previously was used
as perfusate for a resting hind limb preparation, or in rat plasma which was perfused
during electrical stimulation the hind limb. A transferable "exercise factor" could
not be demonstrated; rather the "insulin-like activity" became progressively reduced,
in plasmas previously perfused through resting or electrically stimulated muscle preparations.
Key words
Exercise Factor - Insulin-Like Activity - Muscle Perfusion - Glucose Uptake - Hind
Limb - Hemidiaphragm
1 This work was supported by Grant Number U-1960 from the Health Research Council of
the City of New York.
2 Present address: City of Hope Medical Center, Duarte, California 91010, USA