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Horm Metab Res 1972; 4(5): 325-327
DOI: 10.1055/s-0028-1094025
DOI: 10.1055/s-0028-1094025
Originals
© Georg Thieme Verlag KG Stuttgart · New York
Glycolytic Intermediates in Human Adipose Tissue of Diabetic and Obese Patients During Glucose Tolerance Tests
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
07. Januar 2009 (online)
Abstract
The levels of glucose-6-phosphate and L-glycerol 3-phosphate have been measured in adipose tissue of adult diabetics and non-diabetic obese patients. Despite greatly different blood glucose concentrations, the intermediates were maintained at similar levels in adipose tissue of both groups of patients. The levels of both intermediates fluctuated during a glucose tolerance test. This was most marked with glucose-6-phosphate which in diabetics failed to return to initial values after two hours (p < 0.01).
Key words
Human Adipose Tissue - Glucose-6-Phosphate - Glycerol-Phosphate - Diabetes - Obesity
1 Present address: Department of Medicine, St. Bartholomew's Hospital, London, E.C.I (England)