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Horm Metab Res 1973; 5(1): 48-50
DOI: 10.1055/s-0028-1093982
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© Georg Thieme Verlag KG Stuttgart · New York

Effects of Ventromedial Hypothalamic Lesions on Thyroid Secretion Rate in Rats

D. J. Hinman , D. R. Griffith
  • Department of Zoology and Entomology, Iowa State University, Ames, Iowa, USA
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

In male rats bilateral lesions of the ventromedial nucleus of the hypothalamus which cause significant increase in total body weight result in significant reduction in thyroid secretion rate. It is suggested that this reduction in thyroid secretion rate, along with growth hormone deficiency and hyperinsulinemia, may explain the increase in body fat which has been reported to occur in the hypothalamic obese rat.

Key words

Ventromedial Hypothalamic Lesions - Thyroid Secretion Rate - Weight Gain