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Horm Metab Res 1973; 5(3): 213-215
DOI: 10.1055/s-0028-1093955
DOI: 10.1055/s-0028-1093955
Originals
© Georg Thieme Verlag KG Stuttgart · New York
Effect of Oxytocin and Epinephrine on the Adenylate Cyclase Activity of Myometrium from Pregnant Rhesus Monkeys
Further Information
Publication History
Publication Date:
07 January 2009 (online)
Abstract
The effects of oxytocin and epinephrine on the adenyl cyclase activity of myometrial slices from pregnant rhesus monkeys (Macaca mulatta) near term were measured by the conversion of ATP-14C to cyclic AMP-14C. ATP was prelabeled by incubation with adenine-8-14C. In the presence of caffeine, oxytocin at 2.5 and 5.0 × 10-8M concentrations stimulated adenyl cyclase activity to the same extent. Epinephrine, 1 × 10-7M, also caused an increase in the adenyl cyclase activity in the presence of caffeine.
Key words
Pregnant Rhesus - Myometrium - Oxytocin - Epinephrine - Adenylate Cyclase