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Horm Metab Res 1973; 5(5): 316-321
DOI: 10.1055/s-0028-1093934
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© Georg Thieme Verlag KG Stuttgart · New York

Release of Peripherally Stored Insulin During Acute Muscular Work in Man[*]

P.  Dieterle , B.  Birkner , K.-H.  Gmeiner , P.  Wagner , F.  Erhardt , J.  Henner , C.  Dieterle
  • III. Medizinische Abteilung, Städtisches Krankenhaus München-Neuperlach, and
    II. Medizinische Klinik, University of München, Germany
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

Exercise enhanced the uptake of glucose and FFA in healthy men. The arteriovenous insulin gradients were positive at rest and in the recovery period. During and after exercise the arteriovenous insulin differences reversed, regardless whether the insulin concentrations were elevated or not. The reversal of the arteriovenous insulin differences during and after exercise is consistent with a release of insulin from peripheral stores. The mechanism of exercise enhanced uptake of both glucose and FFA are discussed.

Key words

Muscle Metabolism - Exercise - Glucose and FFA Uptake - Peripheral Release of Insulin

1 Supported by the Deutsche Forschungsgemeinschaft.

1 Supported by the Deutsche Forschungsgemeinschaft.