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Horm Metab Res 1975; 7(2): 190-194
DOI: 10.1055/s-0028-1093776
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© Georg Thieme Verlag KG Stuttgart · New York

Urinary Cyclic AMP and Cyclic GMP Excretion During the Menstrual Cycle

M.  Lebeau , J. E. Dumont , J.  Golstein
  • Institut de Recherche Interdisciplinaire (LMN), School of Medicine, Free University of Brussels, Brussels, Belgium
    Biology Department, Euratom (Publication n° B10 999)
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Publication History

Publication Date:
23 December 2008 (online)

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Abstract

Cyclic AMP and cyclic GMP daily excretion was measured in urine using specific radioimmunoassays, during 12 normal menstrual cycles. Wide day to day variations for both nucleotides were observed. In 6 out of the 12 women, an elevation of urinary cyclic AMP excretion occurred around the ovulatory phase, paralleled by cyclic GMP in 5 cases. Urinary cyclic GMP was higher during the second phase of the cycle in 10 out of 12 women. Daily variations of urinary cyclic AMP and cyclic GMP measured over a long period did not appear to be associated.

Key words

Menstrual Cycle - Cyclic AMP - Cyclic GMP - Urinary Excretion