Failure of 5-Hydroxytryptophan to Stimulate Prolactin and Growth Hormone Secretion in Man

S. Handwerger; J. W. Plonk; H. E. Lebovitz; C. H. Bivens; J. M. Feldman

doi:10.1055/s-0028-1093741

Hormone and Metabolic Research, Inhaltsverzeichnis

Horm Metab Res 1975; 7(3): 214-216
DOI: 10.1055/s-0028-1093741

Originals

Failure of 5-Hydroxytryptophan to Stimulate Prolactin and Growth Hormone Secretion in Man[*]

S. Handwerger , J. W. Plonk , H. E. Lebovitz , C. H. Bivens , J. M. Feldman

Departments of Pediatrics and Medicine, Duke University Medical Center and the Veterans Administration Hospital, Durham, North Carolina, USA

Abstract

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Abstract

The effect of 200 mg 5-hydroxytryptophan (5-HTP) on prolactin and growth hormone secretion in six normal subjects did not differ significantly from the effect of placebo alone. Therefore, 5-HTP would not be a useful provocative stimulus to study prolactin and growth hormone secretion in man.

Key words

5-Hydroxytryptophan - Prolactin - Growth Hormone

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Referenzen

1 Supported by a grant (MO1-RR-30) from the Clinical Research Center Branch, Division of Research Facilities and Resources, grants (AM-01324, 5 TI-AM-5074, AM-5620), from the National Institute of Arthritis, Metabolic, and Digestive Diseases, and a Clinical Investigatorship (2650-01) from the Durham Veterans Administration Hospital (JMF).