Serum Alanine Concentration in Diabetic Children under Insulin Treatment

Abstract

To investigate the response of serum alanine concentration to the diabetic state in children under insulin treatment, three groups of children were examined. These groups consisted of 10 normal children fed for 3 days a high protein diet (Group A), followed by a high carbohydrate diet for 3 days (Group B) and 22 children with diabetes mellitus receiving insulin treatment (Group C). Serum alanine concentration of the diabetic children (509 ± 13 µM) was approximately the same as that in normal children under the high protein diet for 3 days (511 ± 30 µM) but was significantly less than that in normal children under a high carbohydrate diet for 3 days (921 ± 76.9 µM). Blood pH of the diabetic children was not different from that of the normal children under a high carbohydrate diet but was significantly higher than the pH of the normal children under a high protein diet.

Serum Alanine - Children Diabetes