Radioimmunoassay for Human Antithyroglobulin Antibodies of Different Immunoglobulin Classes

G. Delespesse; C. Hubert; Ph. Gausset; A. Govaerts

doi:10.1055/s-0028-1093692

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Horm Metab Res 1976; 8(1): 50-54
DOI: 10.1055/s-0028-1093692

Originals

Radioimmunoassay for Human Antithyroglobulin Antibodies of Different Immunoglobulin Classes

G. Delespesse¹ , C. Hubert² , Ph. Gausset¹ , A. Govaerts¹

¹Immunology and Blood Transfusion Laboratory, Hopital Universitaire St Pierre, Brussels, Belgium
²Department of Internal Medicine, Hopital Universitaire St Pierre, Brussels, Belgium

Further Information

Publication History

Publication Date:
23 December 2008 (online)

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Abstract

A simple, accurate, co-precipitation radioimmunoassay for the detection of anti-thyroglobulin antibodies is described. This semi automated technique allows the determination of the three classes of antibodies; it compares favorably with the tanned red cell hem agglutination test. Its clinical relevance is illustrated in the investigation of various thyroid diseases.

Key words

Radioimmunoassay - Anti-thyroglobulin - Antibodies - IgG - IgA - IgM