Abstract
In seven normal subjects the repeated oral administration of metergoline, a specific
antiserotonin agent, has enhanced HGH response to arginine infusion. Following placebo
administration, arginine-induced HGH release was slightly but not significantly reduced;
similarly, in eight metergoline treated subjects, HGH response to oral L-Dopa was
slightly but not significantly reduced. HGH response to i.v. L-Dopa was not modified
by the drug.
These results suggest that serotonin controls HGH response only in response to arginine,
not to L-Dopa.
Key words
Metergoline - Serotonin - Growth Hormone - Arginine - L-Dopa - Antiserotonin Agents
