Abstract
Circulating levels of immunoreactive parathyroid hormone (PTH) were estimated in fifteen
normal subjects and twenty-five subjects suffering from skeletal fluorosis, ten of
whom had associated endemic genu valgum. Levels of PTH were high in all the subjects
with fluorosis as compared to normals, but among fluorosis subjects, those who had
endemic genu valgum had values strikingly higher than those without. It is suggested
that secondary hyperparathyroidism may have a significant role to play in the pathogenesis
of osteoporosis seen in patients with endemic genu valgum.
Key words
Immunoreactive Parathyroid Hormone - Fluorosis - Osteoporosis - Genu Valgum
