Abstract
Following pyloric ligation, serum immunoreactive gastrin levels and gastric acid accumulation
in acutely thyroidectomized rats with autotransplanted parathyroid glands were significantly
higher than those in thyroid intact rats. Furthermore, serum immunoreactive gastrin
levels were higher in the absence than in the presence of the thyroid gland following
the oral administration of glycine or rat chaw.
These results suggest that endogeneous calcitonin has an inhibitory action on gastric
acid secretion probably through the inhibitory action on gastrin secretion in rats.
Key words
Endogenous Calcitonin - Gastric Acid - Gastrin
