Download PDF
Horm Metab Res 1978; 10(5): 425-428
DOI: 10.1055/s-0028-1093406
Originals

© Georg Thieme Verlag KG Stuttgart · New York

Prenatal Development of Acid β-Glycosidases in the Rat Liver, Effect of Triiodothyronine or Cortisone Administered to Pregnant Rats

Carolyn  Horowitz , H. C. Lau , Jocelyn  Jumawan , O.  Koldovsky
  • Division of Biochemical Development and Molecular Diseases, Children's Hospital of Philadelphia, and the Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, U.S.A.
Further Information

Publication History

Publication Date:
23 December 2008 (online)

Also available at
  PDF Download  Permissions and Reprints

Abstract

We have found that acid β-galactosidase, β-glucuronidase and N-acetyl-β-glucosaminidase in the rat fetal liver increase during the last week of pregnancy. These enzyme activities were influenced by treatment of pregnant rats (daily from day 16) with L-tri-iodothyronine (20 or 50 µg/100 gm b.w.) or cortisone acetate (10 or 50 mg/100 gm b.w.) as studied in their fetuses obtained on day 22 by caesarian section.

Key words

Rat Fetus - Acid β-Glycosidases - L-Tri-Iodothyronine - Cortisone

      >