Zusammenfassung
Venöse Thromboembolien (VTE) führen nicht nur in operativen, allgemeininternistischen
oder onkologischen Fachbereichen, sondern auch in der Palliativmedizin zu erheblicher
Mortalität, Morbidität und Symptomlast. Die thromboemboliespezifischen Belastungen
zu verhindern bzw. zu behandeln und dennoch die veränderten therapeutischen Prioritäten
vor dem Hintergrund der letzten Lebensphase voranzustellen, stellt eine besondere
Herausforderung in der Palliativmedizin dar. Diese Übersicht versucht, relevante Standards
der allgemeinen Thromboemboliebehandlung und -prophylaxe und aktuelle hämostaseologische
Aspekte onkologischer Grunderkrankungen so darzustellen, dass eine ausgewogene Bewertung
in der palliativmedizinischen Therapieentscheidung erleichtert wird.
Abstract
Venous thromboembolism (VTE) leads to substantial mortality, morbidity and symptom
burden not only in operative, medical or oncological, but also in palliative care
settings. To prevent and treat these symptoms but to keep shifting priorities regarding
aspects of end of life care in mind remains a major challenge in palliative care.
This review article summarizes relevant standards for VTE treatment and prophylaxis,
includes updated haemostaseologic insights in the care of cancer patients, and thereby
tries to promote a balanced therapeutic assessment of palliative care decisions.
Schlüsselwörter
Thromboembolie - Primär- / Sekundärprophylaxe - Primärtherapie - Symptome
Key words
thromboembolism - primary / secondary prophylaxis - primary treatment - symptoms
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Dr. med. Bernd Alt-Epping
Abteilung Palliativmedizin, Zentrum Anaesthesiologie, Rettungs- und Intensivmedizin,
Georg-August-Universität Göttingen
Robert Koch-Straße 40
37075 Göttingen
Telefon: ++49-551-39 10501
Fax: ++49-551-39 10502
eMail: bernd.alt-epping@med.uni-goettingen.de
