Geburtshilfe Frauenheilkd 2008; 68 - PO_Endo_02_14
DOI: 10.1055/s-0028-1089029

Dinner Cancelling and its effect on nocturnal Growth-Hormone Kinetics

P Frigo 1, J Ott 2, K Renezeder 1, W Eppel 1, J Huber 1
  • 1Universitätsklinik für Frauenheilkunde, Medizinische Universität Wien, Wien, Österreich
  • 2Universitätsklinik für Gynäkologie und Geburtshilfe, Medizinische Universität Wien, Wien, Österreich

Aims: Dinner Cancelling (DC) is believed to be a powerful change in lifestyle and is offered regularly to patients. The aim of our study was to clarify whether its lipolytic effects are attributed to changes in nocturnal growth hormone (GH) kinetics. Methods: The preliminary results of our pilot-study include 8 female probands having undergone DC on day 1 (standardized meal at 5pm) and eaten a late evening meal (7pm) on day 2. GH was measured every hour from 7pm until 1am. Results: 7 out of 8 probands showed the maximum GH level after DC. A significant difference was found for maximum GH levels on day 1 and 2 (p<0.05). Initial GH values were similar on day 1 and 2 (0.40±0.53 vs. 0.41±0.43, respectively). After DC GH kinetics showed their maximum at midnight (5.25±6.61ng/ml). Conclusion: DC leads to a nocturnal elevation of circulating GH and may thereby lead to lipolysis, muscle build-up, and reduction of protein catabolism.