Geburtshilfe Frauenheilkd 2008; 68 - PO_Onko_02_41
DOI: 10.1055/s-0028-1089008

Long-term Disease-free Survival After Hormonal Therapy of a Patient with Recurrent Low Grade Endometrial Stromal Sarcoma

O Alkasi 1, I Meinhold-Heerlein 2, R Zaki 3, P Fasching 3, N Maass 4, W Jonat 1
  • 1Universitätsklinikum Schleswig-Holstein, Campus Kiel, Klinik Gynäkologie u. Geburtshilfe, Kiel
  • 2Klinik für Gynäkologie und Geburtshilfe, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel
  • 3Frauenklinik der Universität Erlangen, Erlangen
  • 4Universitätsfrauenklinik Kiel, UK-SH, Campus Kiel, Kiel

Background: Approximately 50% of patients with low-grade endometrial stromal sarcoma (ESS) develop recurrent disease including mainly metastases of pelvis and lung. A solitary pulmonary metastasis of this disease is a rare phenomenon.

Case: After initial surgical treatment in 1990, a 28 years old female developed solitary metastases of the lung in 1998 and 1999 which were surgically removed both times. The patient was then treated with goserelin for two years followed by anastrozole to date. She has since been disease-free.

Conclusions: This case report emphasizes the importance of long-term follow-up and initial surgical treatment of low grade ESS and suggests systemic hormonal therapy in case of recurrence.