Two New Isomeric α-Tetralones from Pyrola calliantha

Abstract

Callianthones A (1) and B (2), a pair of new isomeric α-tetralones, together with a known α-tetralone (3) and four known flavonoids (4 – 7) were isolated from the 50 % EtOH extract of Pyrola calliantha. The structures and absolute configurations of the two new isomers were established to be (2S,4R)- and (2S,4S)-2,4-dihydroxy-2,7-dimethyl-3,4-dihydronaphthalen-1(2H)-one (1 and 2, respectively) on the basis of spectral analysis, including 2 D NMR, model studies, and CD spectra.

Pyrola calliantha - Pyrolaceae - α-tetralone - callianthone A - callianthone B

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