Planta Med 2008; 74(15): 1826-1828
DOI: 10.1055/s-0028-1088328
Letter
Natural Products Chemistry
© Georg Thieme Verlag KG Stuttgart · New York

Two New Isomeric α-Tetralones from Pyrola calliantha

Yi-Lei Chen1 , Chang-Heng Tan1 , Jun-Jie Tan1 , Shi-Jin Qu1 , Shan-Hao Jiang1 , Da-Yuan Zhu1
  • 1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Science, Chinese Academy of Sciences, Shanghai, P. R. China
Further Information

Publication History

Received: May 22, 2008 Revised: August 18, 2008

Accepted: August 28, 2008

Publication Date:
07 November 2008 (online)

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Abstract

Callianthones A (1) and B (2), a pair of new isomeric α-tetralones, together with a known α-tetralone (3) and four known flavonoids (4 – 7) were isolated from the 50 % EtOH extract of Pyrola calliantha. The structures and absolute configurations of the two new isomers were established to be (2S,4R)- and (2S,4S)-2,4-dihydroxy-2,7-dimethyl-3,4-dihydronaphthalen-1(2H)-one (1 and 2, respectively) on the basis of spectral analysis, including 2 D NMR, model studies, and CD spectra.

References

Prof. Da-Yuan Zhu

Shanghai Institute of Materia Medica

Chinese Academy of Sciences

555 Zu Chong Zhi Road

Shanghai 201203

People’s Republic of China

Phone: +86-21-5080-6728

Fax: +86-21-5080-7088

Email: dyzhu@mail.shcnc.ac.cn