Synthesis 2009(9): 1459-1462  
DOI: 10.1055/s-0028-1088161
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Novel and Efficient Methods for the Synthesis of Symmetrical Trisulfides

Ahmet Kertmenb, Slawomir Lacha, Janusz Rachona, Dariusz Witt*a
a Department of Organic Chemistry, Chemical Faculty, Gdansk University of Technology, Narutowicza 11/12, 80-952 Gdansk, Poland
Fax: +48(58)3472694; e-Mail: [email protected];
b Chemistry Department, Faculty of Arts and Sciences, Osmangazi University, 26040 Eskisehir, Turkey
Weitere Informationen

Publikationsverlauf

Received 5 November 2008
Publikationsdatum:
25. März 2009 (online)

Abstract

We have developed convenient methods for the synthesis of symmetrical trisulfides under mild conditions in very good yields. The described methods are based on the straightforward preparation of (5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorin-2-yl)disulfanyl derivatives from readily available 5,5-dimethyl-2-sulfanyl-2-thioxo-1,3,2-dioxaphosphorinane or bis(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl) disulfide. The symmetrical trisulfides can be obtained from aliphatic and aromatic thiols and also l-cysteine derivatives.

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