Skull Base 2008; 18(6): 395-399
DOI: 10.1055/s-0028-1087221

© Thieme Medical Publishers

Cerebrospinal Fluid Rhinorrhea Secondary to Ecchordosis Physaliphora

Adebayo Alli1 , Matthew Clark2 , Nicholas J. Mansell3
  • 1Department of Anatomy, Academic Centre, Henriette Raphael Building, Guy's Campus, King's College, London, United Kingdom
  • 2Department of Otolaryngology, John Radcliffe Hospital, Oxford, United Kingdom
  • 3Department of Otolaryngology, Royal Berkshire Hospital, Reading, Berkshire, United Kingdom
Further Information

Publication History

Publication Date:
07 October 2008 (online)


Ecchordosis physaliphora is a rare hamartomatous lesion of notochord origin that is usually asymptomatic. In this case report, such a lesion arose at the clivus, with extension through to the sphenoid sinus. As a result, it presented with cerebrospinal fluid rhinorhea, making the case particularly unusual. We describe the treatment for this rare situation and discuss its differentiation from chordoma, its malignant counterpart.


Dr. Adebayo Alli, M.B.B.Ch. 

Honorary Anatomy Demonstrator, Department of Anatomy, Academic Centre, Henriette Raphael Building

Guy's Campus, King's College, London SE1 1UL, United Kingdom

Email: [email protected]