Planta Med 2008; 74 - PB108
DOI: 10.1055/s-0028-1084453

New vismione from berries of Vismia reichardtiana (O. Ktze) Ewan

LMB Torres 1, SG Pereira 2, RNM Guerra 2
  • 1Instituto de Botânica, Secretaria do Meio Ambiente, São Paul, 04301–012, SP, Brasil
  • 2Centro de Ciências da Saúde, Universidade Federal do Maranhão 65085–580 MA S. Luís MA, Brasil

The berries of species of the genus Vismia are rich in prenylated anthranoids [1]. Vismia reichardtiana, a tree popular in São Luís –MA, northeastern part of Brazil, is known under the name of „lacre“ and is used as a topical remedy for skin diseases [2]. The aqueous, methanol, ethanol and chloroform extracts of berries of V. reichardtiana were immunosuppressant in in vivo and in vitro assays [3]. The partitioning of the chloroform extract (CHCl3/H2O) furnished a yellow solid residue, that was submitted to successive crystallization (EtOAc and MeOH). The structure of the yellow solid (1) was elucidated by 1D NMR, DEPT, IR and GC/MS experiments. ADEPT spectrum analysis (Varian, UNITyplus- 300 'inoval“) showed five CH (δ: 124.3, 123.8,122.7,122.1 and 102.2), five CH2 (δ: 68.3, 30.1, 28.6, 25.9 and 24.6) and six CH3 (δ:26.3, 26.1, 18.6, 18.5, 17.1 and 14.6).

Acknowledgements: FAPESP/SP, CNPq.

References: 1. Pinheiro, M.R. et al. (1984), Phy. 23: 1737–1740. 2. Gonçalves, M.L.S. et al. (1981). Phy. 20:1947–1950. 3. Guerra, R.N.M. E. (1997) PhD, Thesis, USP, São Paulo, Brasil