Planta Med 2008; 74 - PB89
DOI: 10.1055/s-0028-1084434

Flavonoids from Bupleurum montanum Coss. (Apiaceae)

M Benahmed 1, A Elomri 1, S Akkal 2, H Laouar 3, P Vérité 4, E Seguin 1
  • 1Université de Rouen, UMR CNRS 6014, COBRA, UFR Médecine-Pharmacie, 22 Bd Gambetta, 76000 Rouen, France
  • 2Département de Chimie, Université Mentouri, Route de Ain el Bey, Constantine 25000, Algérie
  • 3Département de Biologie, Faculté de Sciences, Université Ferhat Abbes, Setif 19000, Algérie
  • 4Université de Rouen, Laboratoire de Chimie Analytique ADEN 3234, UFR Médecine-Pharmacie, 22 Bd Gambetta, 76000 Rouen, France

In continuation of our studies on Algerian Apiaceous plants [1] we report here a phytochemical study of aerial parts of Bupleurum montanum, an Algerian endemic species [2], collected from Megress Mountain (Eastern Algeria) at 1500m above sea level, during June 2006. Quercitin 1 [3] and tamarixetin 2 [4] were isolated from the ethylacetate extract. Isorhamnetin-3-rutinoside 3 [5], originally isolated from the flowers of Narcissus tazetta [6], and kaempferol-3-rutinoside 4 [4] were obtained from the n-butanol extract. The structural elucidation was performed mainly by MS, 1D and 2D NMR spectrum data.

R 1

R 2

R 3

1

H

H

OH

2

H

CH3

OH

3

Rha (1 → 6) Glc

H

OCH3

4

Rha (1 → 6) Glc

H

H

References: 1. Benahmed, M. et al. (2006) Biochem. Syst. Ecol. 34: 645–647.

2. Quezel, P., Santa, S. (1963) Nouvelle flore de l'Algérie et des régions désertiques méridionales, Tome II. Edition CNRS, Paris.

3. Bilia, A. R. et al. (1996) Pharm. Acta Helv. 71: 99–204.

4. Alejandro, A.F. et al. (1998) Phytochemistry 48: 1237–1240.

5. Sang, S. et al. (2002)J. Agric. Food Chem. 50: 2459–2463.

6. Kubota, T., Hase, T. (1956)J. Inst. Polytech., Osaka City Univ. Ser. C, 5: 49.