Planta Med 2008; 74 - PB86
DOI: 10.1055/s-0028-1084431

New acyl-glucosylsterol with unusual fatty acids from Ficus exasperata

MDJ Dongfack 1, 2, J Wandji 2, MC Lallemand 1, F Tillequin 1
  • 1Laboratoire de pharmacognosie, Faculté des Sciences Pharmaceutiques et Biologiques, UMR8638 associée au CNRS, Université Paris Descartes, 4 Av de l'Observatoire 75006 Paris
  • 2Laboratoire de Substances Naturelles, Département de Chimie Organique, Faculté des Sciences, P.O Box 812 Yaounde, Cameroun

Ficus exasperata (Moraceae) is used as acaricide and for the treatment of asthma, furred tongue, throat inflammation and sore throat [1]. It also exhibites antiulcer activity [2]. From the methanol extract of stems of Ficus exasperata Vahl. collected in the centre province of Cameroon, one new unusual fatty acid 1, and one new acyl-glucosylsterol 2, along with several known compounds were isolated. Their structures were elucidated using 1-D and 2-D NMR spectroscopic techniques (DEPT, COSY, HSQC, and NOESY) and mass spectral analysis.

Acknowledgements: One of the authors (M. D. J. Dongfack) is grateful to AUF (Agence Universitaire de la Francophonie) for Doctoral fellowship

References:1. Chhabra, SC. et al. (1984). J Ethnopharmacol. 11:157–179

2. Akah, PA. et al. (1998). J Ethnopharmacol. 62:123–127