New triterpenoids from Drypetes species

J. Wandji; M. D. J. Dongfack; D. D. Chiozem; H. Dufat; F. Tillequin

doi:10.1055/s-0028-1084419

Planta Medica, Inhaltsverzeichnis

New triterpenoids from Drypetes species

J Wandji ¹, MDJ Dongfack ¹^,², DD Chiozem ¹, H Dufat ², F Tillequin ²

¹Laboratoire de Substances Naturelles, Département de Chimie Organique, Faculté des Sciences, P.O Box 812 Yaounde, Cameroun
²Laboratoire de pharmacognosie, Faculté des Sciences Pharmaceutiques et Biologiques, UMR8638 associée au CNRS, Université Paris Descartes, 4 Av de l'Observatoire 75006 Paris

Abstract

As a continuation of our current investigations on bioactive compounds from the Cameroonian Drypetes genus [1–3], eight new triterpenoids (1-8) were isolated from the methanol extract of three species of Cameroonian Drypetes. Drypetes paxii afforded 1, 2, Drypetes tessmanniana afforded 3, 4 and Drypetes inaequalis afforded 5, 6, 7, 8) Their structures were characterised on the basis of spectroscopic methods and chemical evidence.

Acknowledgements: Authors are grateful for the financial support from IFS (International Foundation for Science), grant N° F 2624/3F.

References:1. Chungag-Anye, NB. et al. (2001) Pharmaceutical and Pharmacological Letters 11:61.

2. Chungag-Anye, NB. et al. (2002) Pharmaceutical Biology 41:26.

3. Wansi, JD. et al. (2007) BLACPMA, 6:5.