Planta Med 2008; 74 - PA278
DOI: 10.1055/s-0028-1084276

In vitro anti-amoebic and anti-giardial activity of some medicinal plants of the family Myrtaceae

A Bader 1, I Mosleh 2
  • 1Faculty of Pharmacy, Al-Zaytoonah Private University of Jordan, PO Box 130, 11733 Amman, Jordan
  • 2Department of Biological Sciences, University of Jordan, Amman, Jordan

According to WHO, diarrhea is the passage of 3 or more loose or liquid stools per day. It is usually a symptom of gastrointestinal infection, which can be caused by a variety of microorganism, parasites or viruses. Severe diarrhea leads to fluid loss, and may be life-threatening. Among the causative agents of diarrhea are parasitic protozoan Entamoeba histolytica and Giardia intestinalis. These parasites became recently multidrug resistant, so the finding of new synthetic or natural drugs is of great necessity. We tested the aqueous crude extracts of some medicinal plants belonging to the family Myrtaceae that are used popularly for the treatment of diarrhea [1] such as the Syzygium aromaticum (L.) Merr. & Perry, Eucalyptus camaldulensis Dehnh and the Myrtus communis L. The extracts showed an important degree of inhibition effect against Entamoeba histolytica and Giardia intestinalis. The extracts were not toxic to hep 2 and vero cells at the IC50 concentrations. Results were compared also with metronidazole as shown in the table.


Entamoeba histolytica

Giardia intestinalis

Plant name



Myrtus communis



Eucalyptus camaldulensis



Syzygium aromaticum




References: 1. Duke, J.A. (2003) CRC Handbook of Medicinal, Boca Raton-Florida.