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Synthesis 2008(23): 3783-3786  
DOI: 10.1055/s-0028-1083234
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Simple and Efficient Synthesis of (±)-Equol and Related Derivatives

Atul Gupta*, Suprabhat Ray
Division of Medicinal & Process Chemistry, Central Drug Research Institute, Lucknow 226001, India
e-Mail: atisky2001@yahoo.co.in;
Further Information

Publication History

Received 8 June 2008
Publication Date:
14 November 2008 (online)

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Abstract

A simple and efficient synthesis of (±)-equol and related derivatives in good yields from inexpensive starting materials has been described.

Key words

flavanone - flavone - benzopyran - equol - dehydroequol - estrogen - Grignard reaction - Friedel-Crafts reaction

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1

Present and corresponding address: Département de Chimie-Biologie, Université de Quebec à Trois-Rivières, C.P. 500, Trois-Rivières, QC, G9A 5H7, Canada.

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FDA register 64FR57699; Oct. 26, 1999.