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Hamostaseologie 2025; 45(06): 451
DOI: 10.1055/a-2731-2508
Editorial

Connecting the Dots: Reflections on a vibrant Year in Haemostasis Research

Authors

  • Manuela Albisetti

    1   Abteilung Hämatologie, Universitäts-Kinderspital Zürich – Eleonorenstiftung, Zürich, Switzerland

  • Florian Langer

    2   Gerinnungsambulanz und Hämophiliezentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg. Germany

  • Heiko Rühl

    3   Institut für Experimentelle Hämaotogie und Transfusionsmedizin, Universitätsklinikum Bonn, Bonn, Germany
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Dear Readers,

Another intense and fruitful year for the journal Hämostaseologie – Progress in Haemostasis is drawing to a close. In 2025, we were once again able to cover a wide range of topics – from diagnostic guidelines and the interaction between immunotherapies and haemostasis to women-specific aspects of congenital bleeding disorders. The increasingly close interconnection between basic research, clinical translation and guideline development is striking and makes our journal a lively forum.

Among the most downloaded articles published in 2025, there are three that we would like to highlight as they mark the latest trends in haemostasis research and practice.

The article by Alessandra Bosch et al.[1] focuses on an often-neglected group – women with congenital bleeding disorders. The authors emphasise that gynaecological and obstetric bleeding events are clinically relevant and can significantly affect quality of life. Delayed diagnoses and insufficient consideration in research are critically discussed. This article raises awareness of gender-specific aspects of haemostasis and calls for more consistent consideration of female patients in research and clinical practice.

The article by Jennifer Gebetsberger et al.[2] is a comprehensive guideline for the diagnosis of congenital platelet function disorders. In the article, the newest diagnostic algorithms, structured questionnaires for careful medical history taking and systematic laboratory tests (e.g. light transmission aggregometry, flow cytometry) as well as the use of state-of-the-art genetic methods (NGS) have been extensively reviewed. Particular emphasis was placed on standardisation in pre-analysis in order to improve the validity of the results. These guidelines reflect modern technological possibilities and evidence-based procedures for platelet function tests.

Last but not least, the article by Christina Rolling et al.[3] addresses the interaction between modern immunotherapies – in particular checkpoint inhibitors and CAR-T cells – and the haemostatic system. It examines the effects these therapies have on thrombosis risks, the mechanisms behind them, and how these findings can be taken into account in the clinical management of oncology patients. With the increasing use of immuno-oncological therapies, a relevant interface between oncology and haemostasis is emerging. Understanding these interdisciplinary interactions is crucial for safe and effective therapy planning, especially in high-risk populations. Such an article strengthens the role of our journal as a platform for innovative interface topics.

For the coming year, we will continuously strive to make publication processes efficient in order to accelerate knowledge transfer. One aim is to further expand the bridge between cutting-edge research and clinical application. Another aim is to maintain the high quality of contributions in order to continue positioning ourselves as media leaders in the field of haemostasis, not only in German-speaking countries but increasingly at an international level.

Manuela Albisetti, Florian Langer and Heiko Rühl for the editorial team



Publication History

Article published online:
08 January 2026

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