J Neurol Surg B Skull Base
DOI: 10.1055/a-2706-1319
Original Article

Endoscopic Transsphenoidal Selective Resection of the Medial Wall of the Cavernous Sinus for the Treatment of Functional Pituitary Adenomas

Authors

  • Xuanzhi Wang

    1   Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
  • Cheng Xufeng

    1   Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
  • Zheng Li

  • Fei Wang

    1   Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China

Funding Information This study was financially supported by the Anhui Provincial Natural Science Foundation (2308085MH279), Medical Leading Technology of the First Affiliated Hospital of the University of Science and Technology of China (2023LXJS-13), and 2021 Anhui Provincial Quality Engineering Project for Higher Education Institutions (2021jyxm1778).
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Abstract

Objective

To investigate the efficacy of endoscopic transsphenoidal selective resection of the medial wall of the cavernous sinus (MWCS) for the treatment of functional pituitary adenomas (FPAs).

Methods

Clinical data of fifteen patients with FPAs were retrospectively analyzed. The MWCS on the side of the tumor was surgically resected.

Results

In this study of fifteen patients, endocrine remission was observed in thirteen cases (86.7%) after surgery, and tumor cells in the MWCS were found in ten (66.7%) cases. No serious postoperative complications occurred in any patient.

Conclusion

For FPAs characterized as Knosp grades 0 to 3, if there is no clear pseudocapsule or normal pituitary between the tumor and the MWCS during the operation, consideration of removal of the MWCS on that side may contribute to improved postoperative remission rates.

These authors contributed equally to this article.




Publikationsverlauf

Eingereicht: 28. April 2025

Angenommen: 18. September 2025

Accepted Manuscript online:
22. September 2025

Artikel online veröffentlicht:
07. Oktober 2025

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