Open Access
CC BY 4.0 · Arch Plast Surg
DOI: 10.1055/a-2668-4004
Original Article

Comprehensive Outcomes of the Keystone Design Perforator Island Flap: A Prospective Study of 121 Consecutive Cases

Sofija Pejkova
1   Plastic Surgery, University Clinical Centre Mother Teresa Skopje, Skopje, North Macedonia (Ringgold ID: RIN123726)
,
Gordana Georgieva
1   Plastic Surgery, University Clinical Centre Mother Teresa Skopje, Skopje, North Macedonia (Ringgold ID: RIN123726)
,
Sofija Tusheva
1   Plastic Surgery, University Clinical Centre Mother Teresa Skopje, Skopje, North Macedonia (Ringgold ID: RIN123726)
,
Katerina Jovanovska
1   Plastic Surgery, University Clinical Centre Mother Teresa Skopje, Skopje, North Macedonia (Ringgold ID: RIN123726)
,
Stefania Azmanova Mladenovska
1   Plastic Surgery, University Clinical Centre Mother Teresa Skopje, Skopje, North Macedonia (Ringgold ID: RIN123726)
,
Bisera Nikolovska
1   Plastic Surgery, University Clinical Centre Mother Teresa Skopje, Skopje, North Macedonia (Ringgold ID: RIN123726)
,
Blagoja Srbov
2   Plastic and reconstructive surgery, University Clinical Centre Mother Teresa Skopje, Skopje, North Macedonia (Ringgold ID: RIN123726)
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The Keystone Design Perforator Island Flap (KDPIF), developed by Behan in 2003, has significantly impacted reconstructive surgery. This technique utilizes angiotomes, which integrate vascular, dermatomal, neural, and lymphatic networks, providing various approaches for complex reconstructions. This study enhances the initial PACE framework (Pain, Aesthetic appearance, Complication rates, Economic feasibility) by adding 'S' for Sensibility, creating the PACES framework to include sensory improvements in the assessment. Our retrospective analysis included 121 patients over 51 months, primarily with defects from skin malignancies (66.9%) and chronic wounds (16.5%), mainly on the trunk (51.2%). The average age was 56.2 years, with males comprising 73.6% of the cohort. Outcome measures included pain, assessed using the Visual Analogue Scale (VAS) at one and twelve months postoperatively, revealing a significant reduction in pain. Aesthetic outcomes were evaluated through the Manchester Scar Scale (MSS), showing notable improvements in scar appearance. Complication rates were low, indicating the safety of the flap in this series. Economic efficiency was assessed by operative time and hospital stay, with shorter durations indicating cost-effectiveness. Sensory outcomes, measured with the Postoperative Flap Sensitivity Self-Assessment Questionnaire, showed substantial gains in sensory function, enhancing patients’ quality of life. The PACES framework facilitated a comprehensive evaluation of KDPIF, confirming its effectiveness across various defect types and patient populations. Our findings support the wider adoption of KDPIFs for reconstructive purposes, alongside ongoing efforts to optimize patient outcomes and functionality.



Publikationsverlauf

Eingereicht: 08. November 2024

Angenommen nach Revision: 26. Juli 2025

Accepted Manuscript online:
30. Juli 2025

© . The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).

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