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DOI: 10.1055/a-2626-9145
Thyroid Storm Triggered by Partial Hydatidiform Mole: A Rare and Life-Threatening Complication
Abstract
A 26-year-old woman, gravida 1 para 0 at 14 weeks' 1-day gestation, presented with vaginal spotting and systemic symptoms, including palpitations, shortness of breath, heat intolerance, nausea, and vomiting for 2 weeks. Workup revealed maternal tachycardia, severe-range blood pressure, elevated beta human chorionic gonadotropin of 2,442,400 mIU/mL, suppressed thyroid stimulating hormone, and elevated T4, consistent with thyroid storm with possible preeclampsia with severe features.[1] A transvaginal ultrasound suggested a partial molar pregnancy; this was later confirmed by surgical pathology. This case highlights the rare yet serious complications of hydatidiform mole, in particular, a partial molar pregnancy, including thyroid storm and superimposed preeclampsia, emphasizing the importance of management at a tertiary care center with a multidisciplinary team to optimize maternal outcomes.[2] [3]
Keywords
partial molar pregnancy - partial hydatidiform mole - thyroid storm - gestational trophoblastic disease - preeclampsia with severe featuresPublication History
Received: 24 March 2025
Accepted: 05 May 2025
Accepted Manuscript online:
06 June 2025
Article published online:
18 June 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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