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DOI: 10.1055/a-2626-9145
Thyroid Storm Triggered by Partial Hydatidiform Mole: A Rare and Life-Threatening Complication

A 26-year-old woman, gravida 1 para 0 at 14 weeks 1-day gestation, presented with vaginal spotting and systemic symptoms, including palpitations, shortness of breath, heat intolerance, nausea, and vomiting for two weeks. Workup revealed maternal tachycardia, severe-range blood pressure, elevated β-hCG of 2,442,400 mIU/mL, suppressed TSH, and elevated T4, consistent with thyroid storm with possible preeclampsia with severe features. A transvaginal ultrasound suggested a partial molar pregnancy; this was later confirmed by surgical pathology. This case highlights the rare yet serious complications of hydatidiform mole, in particular, a partial molar pregnancy, including thyroid storm and superimposed preeclampsia, emphasizing the importance of management at a tertiary care center with a multidisciplinary team to optimize maternal outcomes.
Publication History
Received: 24 March 2025
Accepted after revision: 05 May 2025
Accepted Manuscript online:
06 June 2025
© . The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
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