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DOI: 10.1055/a-2601-9070
Neurologists and Clinical Informatics: Realizing the Potential of Digital Medicine

Abstract
Clinical informatics (CI) is an emerging field within biomedical informatics that sits at the intersection of clinical care, health systems, and health information technology (IT). CI emphasizes how individuals (neurologists, patients, staff) interact with health IT (HIT), with a focus on designing systems that support optimal neurologic care. As neurology becomes more complex—expanding diagnostics, treatments, and subspecialties—there is a growing need for usable, efficient electronic health record systems that enhance, rather than burden, care delivery. This paper reviews roles CI neurologists can play, as translators, architects, advocates, and leaders across clinical, operational, and strategic domains. We highlight examples where CI expertise addresses challenges in neurology, including access to care, documentation burden, burnout, quality improvement, patient engagement, artificial intelligence, research registries, and precision health. With projected workforce shortages in neurology and CI, neurologists with CI expertise will ensure that HIT will effectively support high-quality neurologist-led care.
Keywords
clinical informatics - electronic health records - neurology - health information technology - digital medicinePublication History
Accepted Manuscript online:
07 May 2025
Article published online:
26 May 2025
© 2025. Thieme. All rights reserved.
Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
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References
- 1 Kulikowski CA, Shortliffe EH, Currie LM. et al. AMIA Board white paper: definition of biomedical informatics and specification of core competencies for graduate education in the discipline. J Am Med Inform Assoc 2012; 19 (06) 931-938
- 2 Institute of Medicine (US) Committee on Quality of Health Care in America. To Err Is Human: Building a Safer Health System. In: Kohn L, Corrigan J, Donaldson M. eds. National Academies Press (US); 2000.
- 3 Silverman HD, Steen EB, Carpenito JN, Ondrula CJ, Williamson JJ, Fridsma DB. Domains, tasks, and knowledge for clinical informatics subspecialty practice: results of a practice analysis. J Am Med Inform Assoc 2019; 26 (07) 586-593
- 4 Sittig DF, Singh H. A new sociotechnical model for studying health information technology in complex adaptive healthcare systems. Qual Saf Health Care 2010; 19 (Suppl. 03) i68-i74
- 5 Schor NF. Equipping AI for unbiased and inclusive neurology (limited online). JAMA Neurol 2025; 82 (Suppl. 03) 211-212
- 6 Sarva H, Patino GA, Rashid M, Owens JWM, Robbins MS, Sandrone S. The status of neurology fellowships in the United States: clinical needs, educational barriers, and future outlooks. BMC Med Educ 2021; 21 (01) 108
- 7 Gregory ME, Russo E, Singh H. Electronic health record alert-related workload as a predictor of burnout in primary care providers. Appl Clin Inform 2017; 8 (03) 686-697
- 8 Kotter JP. Leading Change. Harvard Business School Press; 1996
- 9 Ashton M. Getting rid of stupid stuff. N Engl J Med 2018; 379 (19) 1789-1791
- 10
American Academy of Neurology.
Improving Access to Care. Accessed March 9, 2025 at: https://www.aan.com/practice/improving-access-to-care
- 11 Lin CC, Muthukumar L, Reynolds EL, Hill CE, Esper GJ, Callaghan BC. Wait time to see a neurologist after referral among Medicare participants. Neurology 2025; 104 (03) e210217
- 12 Joshi S, Gali K, Radecki L. et al. Integrating quality improvement into the ECHO model to improve care for children and youth with epilepsy. Epilepsia 2020; 61 (09) 1999-2009
- 13 Kirschner N, Greenlee C. The Patient-Centered Medical Home Neighbor: The Interface of the Patient-Centered Medical Home with Specialty/Subspeciality Practices. American College of Physicians; 2010. . Accessed April 27, 2025 at: https://www.acponline.org/sites/default/files/documents/acp_policy/policies/pcmh_interface_subspecialty_practices_2010.pdf
- 14 Outland BE, Greenlee C, Vimalananda V, Candler S, Bering H, Arbaje A. Beyond the Referral: Principles of Effective, Ongoing Primary and Specialty Care Collaboration. American College of Physicians; 2022. . Accessed September 18, 2024 at: https://www.acponline.org/sites/default/files/acp-policy-library/policies/beyond_the_referral_position_paper_2022.pdf
- 15 Bates DW, Singh H. Two decades since to err is human: An assessment of progress and emerging priorities in patient safety. Health Aff (Millwood) 2018; 37 (11) 1736-1743
- 16
American Academy of Neurology.
Quality Improvement. Accessed March 30, 2025 at: https://www.aan.com/practice/quality-improvement-toolkit
- 17 Reynolds EL, Burke JF, Banerjee M, Callaghan BC. Randomized controlled trial of a clinical decision support system for painful polyneuropathy. Muscle Nerve 2020; 61 (05) 640-644
- 18 Campbell R. The five “rights” of clinical decision support. J AHIMA 2013; 84 (10) 42-47 , quiz 48
- 19 Evans RW, Burch RC, Frishberg BM. et al. Neuroimaging for migraine: The American Headache Society Systematic Review and Evidence-Based Guideline. Headache 2020; 60 (02) 318-336
- 20 Loder E, Weizenbaum E, Frishberg B, Silberstein S. American Headache Society Choosing Wisely Task Force. Choosing wisely in headache medicine: the American Headache Society's list of five things physicians and patients should question. Headache 2013; 53 (10) 1651-1659
- 21 Hawasli AH, Chicoine MR, Dacey Jr RGJ. Choosing wisely: a neurosurgical perspective on neuroimaging for headaches. Neurosurgery 2015; 76 (01) 1-5 , quiz 6
- 22 Silberstein SD. Practice parameter: Evidence-based guidelines for migraine headache (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2000; 55 (06) 754-762
- 23
Centers for Medicare & Medicaid Services.
Appropriate Use Criteria Program. Accessed March 30, 2025 at: https://www.cms.gov/medicare/quality/appropriate-use-criteria-program
- 24 Alomar D, Almashmoum M, Eleftheriou I, Whelan P, Ainsworth J. The impact of patient access to electronic health records on health care engagement: Systematic review. J Med Internet Res 2024; 26: e56473
- 25 Delbanco T, Walker J, Bell SK. et al. Inviting patients to read their doctors' notes: a quasi-experimental study and a look ahead. Ann Intern Med 2012; 157 (07) 461-470
- 26
Assistant Secretary for Technology Policy/Office of the National Coordinator for Health
IT.
Information Blocking. Accessed April 9, 2025 at: https://www.healthit.gov/topic/information-blocking
- 27 Yu MM, Weathers AL, Wu AD, Evans DA. Sharing notes with patients: A review of current practice and considerations for neurologists. Neurol Clin Pract 2017; 7 (02) 179-185
- 28
American Academy of Neurology.
Patient Reported Outcome (PRO) Scales and Tools. Accessed April 9, 2025 at: https://www.aan.com/practice/patient-reported-outcome-tools
- 29 Sigsbee B, Bernat JL. Physician burnout: A neurologic crisis. Neurology 2014; 83 (24) 2302-2306
- 30 Busis NA, Shanafelt TD, Keran CM. et al. Burnout, career satisfaction, and well-being among US neurologists in 2016. Neurology 2017; 88 (08) 797-808
- 31 Downing NL, Bates DW, Longhurst CA. Physician burnout in the electronic health record era: Are we ignoring the real cause?. Ann Intern Med 2018; 169 (01) 50-51
- 32 Holmgren AJ, Downing NL, Bates DW. et al. Assessment of electronic health record use between US and Non-US health systems. JAMA Intern Med 2021; 181 (02) 251-259
- 33 Rule A, Bedrick S, Chiang MF, Hribar MR. Length and redundancy of outpatient progress notes across a decade at an academic medical center. JAMA Netw Open 2021; 4 (07) e2115334
- 34 American Medical Informatics Association. AMIA 25x5 Reducing Documentation Burden Toolkit. 2021 . Accessed April 9, 2025 at: https://brand.amia.org/m/3aaa0f687a601441/original/25x5-toolkit.pdf
- 35 Weathers AL, Haq IU, Ficker DM, Ney JP, Meyers SL. Neurology steering board effects change for a major electronic health record vendor. Neurol Clin Pract 2019; 9 (04) 360-364
- 36 American Medical Association. Augmented Intelligence in Health Care. 2018 . Accessed April 8, 2025 at: https://www.ama-assn.org/system/files/2019-01/augmented-intelligence-policy-report.pdf
- 37
Moura Junior V,
Kummer B,
Moura LMVR.
Population health in neurology and the transformative promise of artificial intelligence
and large language models. Semin Neurol 2025 (ahead of publication)
- 38
American Heart Association.
Get With the Guidelines-Stroke. Accessed April 22, 2025 at: https://www.heart.org/en/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-stroke
- 39
University of California SF.
BrainHealth Registry. Accessed April 22, 2025 at: https://www.brainhealthregistry.org/
- 40
West Virginia University.
West Virginia Alzheimer Disease Registry. Accessed April 22, 2025 at: https://wvadr.hsc.wvu.edu/
- 41
California Department of Public Health.
California Parkinson's Disease Registry. Accessed April 22, 2025 at: https://www.cdph.ca.gov/Programs/CCDPHP/DCDIC/CDSRB/Pages/California-Parkinson's-Disease-Registry.aspx
- 42
Centers for Medicare & Medicaid Services.
Monoclonal Antibodies Directed Against Amyloid for the Treatment of Alzheimer's Disease
CED Study Registry. Accessed April 22, 2025 at: https://qualitynet.cms.gov/alzheimers-ced-registry
- 43 Wu AD, Wilson AM. Parkinson's disease population-wide registries in the United States: Current and future opportunities. Front Digit Health 2023; 5: 1149154
- 44
Observational Health Data Sciences and Informatics (OHDSI).
Observational Health Data Sciences and Informatics. Accessed April 22, 2025 at: https://www.ohdsi.org/
- 45
i2b2 Foundation.
Informatics for Integrating Biology and the Bedside (i2b2). Accessed April 22, 2025
at: https://www.i2b2.org/
- 46 Wilkinson MD, Dumontier M, Aalbersberg IJ. et al. The FAIR Guiding Principles for scientific data management and stewardship. Sci Data 2016; 3: 160018
- 47 Strzelczyk A, Schubert-Bast S. Psychobehavioural and cognitive adverse events of anti-seizure medications for the treatment of developmental and epileptic encephalopathies. CNS Drugs 2022; 36 (10) 1079-1111
- 48 Majersik JJ, Ahmed A, Chen IA. et al. A shortage of neurologists - We must act now: A report from the AAN 2019 Transforming Leaders Program. Neurology 2021; 96 (24) 1122-1134
- 49 Bassetti CLA, Accorroni A, Arnesen A. et al. General neurology: Current challenges and future implications. Eur J Neurol 2024; 31 (06) e16237
- 50 NORC at the University of Chicago, American Health Information Management Association (AHIMA). Health Information Workforce: Survey Results on Workforce Challenges and the Role of Emerging Technologies. 2023 . Accessed April 22, 2025 at: https://norc.org/content/dam/norc-org/pdf2023/AHIMA-Workforce-Survey-Report-Final-2023.pdf
- 51 Hersh WR, Boone KW, Totten AM. Characteristics of the healthcare information technology workforce in the HITECH era: underestimated in size, still growing, and adapting to advanced uses. JAMIA Open 2018; 1 (02) 188-194
- 52
The American Board of Preventive Medicine.
Clinical Informatics Certification. Accessed April 22, 2025 at: https://www.theabpm.org/become-certified/subspecialties/clinical-informatics/
- 53 Desai S, Mostaghimi A, Nambudiri VE. Clinical informatics subspecialists: characterizing a novel evolving workforce. J Am Med Inform Assoc 2020; 27 (11) 1711-1715
- 54
Healthcare Information and Management Systems Society.
Certified Professional in Healthcare Information and Management Systems (CPHIMS).
Accessed April 22, 2025 at: https://www.himss.org/certifications/cphims/
- 55
American Medical Informatics Association.
AMIA Health Informatics Certification (AHIC). Accessed April 22, 2025 at: https://amia.org/careers-certifications/amia-health-informatics-certification-ahic
- 56
Institute for Healthcare Improvement.
Institute for Healthcare Improvement (IHI). Accessed April 22, 2025 at: https://www.ihi.org/