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CC BY 4.0 · Surg J (N Y) 2025; 11: a25914143
DOI: 10.1055/a-2591-4143
Case Report

Pancreatic Metastasis from Renal Cell Carcinoma Several Years after Nephrectomy: Two Case Reports and Literature Review

Authors

  • Souad Ghattas

    1   Department of General Surgery, Saint Georges Hospital University Medical Center/University of Balamand, Beirut, Lebanon

  • Jad El Bitar 

    1   Department of General Surgery, Saint Georges Hospital University Medical Center/University of Balamand, Beirut, Lebanon

  • Hani Maalouf

    1   Department of General Surgery, Saint Georges Hospital University Medical Center/University of Balamand, Beirut, Lebanon

  • Tarek Bulbul 

    1   Department of General Surgery, Saint Georges Hospital University Medical Center/University of Balamand, Beirut, Lebanon

  • Omar Tabbikha

    1   Department of General Surgery, Saint Georges Hospital University Medical Center/University of Balamand, Beirut, Lebanon

  • Wissam Dib 

    2   Department of General Surgery, Saint Georges Hospital University Medical Center, Beirut, Lebanon

  • Antoine El Asmar 

    2   Department of General Surgery, Saint Georges Hospital University Medical Center, Beirut, Lebanon

  • Hind Rahban

    3   Laboratory Department, Lebanese American University Medical Center, Beirut, Lebanon

  • Ziad El Rassi

    2   Department of General Surgery, Saint Georges Hospital University Medical Center, Beirut, Lebanon

Funding None.
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Abstract

Metastases of renal cell carcinoma (RCC) to the pancreas are infrequent, comprising only 1 to 4% of pancreatic malignancies. These cases are distinguished by a prolonged period of being free from the disease following the initial surgery. We present here two rare cases of isolated pancreatic metastases from RCC, occurring 7 to 8 years after nephrectomy. The patients were asymptomatic; the masses were discovered incidentally during their routine annual health checkup. Surgical resection of these oligometastases was the appealing choice for managing these cases, potentially complemented by systemic treatment. The late onset of metastasis from RCC in solid organs should always be considered when dealing with patients with a history of RCC. Additionally, the follow-up following nephrectomy for RCC should be extended over 10 years.

Keywords

renal cell carcinoma - pancreatic metastasis - pancreatectomy - metastasectomy - late onset

Ethical Approval

Case report approved for publishing by Ethical Committee at the Saint George Hospital University Medical Center, and Head of General Surgery Division.


Data Availability Statement

All data were obtained from the patient for publication of this case report and accompanying images. All data are available for review by the Editor-in-Chief of this journal on request.




Publikationsverlauf

Eingereicht: 04. Dezember 2024

Angenommen: 17. April 2025

Artikel online veröffentlicht:
20. Mai 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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Bibliographical Record
Souad Ghattas, Jad El Bitar, Hani Maalouf, Tarek Bulbul, Omar Tabbikha, Wissam Dib, Antoine El Asmar, Hind Rahban, Ziad El Rassi. Pancreatic Metastasis from Renal Cell Carcinoma Several Years after Nephrectomy: Two Case Reports and Literature Review. Surg J (N Y) 2025; 11: a25914143.
DOI: 10.1055/a-2591-4143
 

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