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DOI: 10.1055/a-2547-6645
Artificial intelligence-assisted esophagogastroduodenoscopy improves procedure quality for endoscopists in early stages of training
Gefördert durch: Research Grants Council, University Grants Committee 8601414 Clinical Trial: Registration number (trial ID): NCT04883567, Trial registry: ClinicalTrials.gov (http://www.clinicaltrials.gov/), Type of Study: Prospective

Abstract
Background and study aims
Completeness of esophagagogastroduodenoscopy (EGD) varies among endoscopists, leading to a high miss rate for gastric neoplasms. This study aimed to determine the effect of the Cerebro real-time artificial intelligence (AI) system on completeness of EGD for endoscopists in early stages of training.
Patients and methods
The AI system was built with CNN and Motion Adaptive Temporal Feature Aggregation (MA-TFA). A prospective sequential cohort study was conducted. Endoscopists were taught about the standardized EGD protocol to examine 27 sites. Then, each subject performed diagnostic EGDs per protocol (control arm). After completion of the required sample size, subjects performed diagnostic EGDs with assistance of the AI (study arm). The primary outcome was the rate of completeness of EGD. Secondary outcomes included overall inspection time, individual site inspection time, completeness of photodocumentation, and rate of positive pathologies.
Results
A total of 466 EGDs were performed with 233 in each group. Use of AI significantly improved completeness of EGD [mean (SD) (92.6% (6.2%) vs 71.2% (16.8%)]; P <0.001 (95% confidence interval 19.2%–23.8%, SD 0.012). There was no difference in overall mean (SD) inspection time [765.5 (338.4) seconds vs 740.4 (266.2); P=0.374]. Mean (SD) number of photos for photo-documentation significantly increased in the AI group [26.9 (0.4) vs 10.3 (4.4); P <0.001]. There was no difference in detection rates for pathologies in the two groups [8/233 (3.43%) vs 5/233 (2.16%), P=0.399].
Conclusions
Completeness of EGD examination and photodocumentation by endoscopists in early stages of are improved by the AI-assisted software Cerebro.
Keywords
Quality and logistical aspects - Training - Image and data processing, documentatiton - Quality managementPublikationsverlauf
Eingereicht: 04. Oktober 2024
Angenommen nach Revision: 11. Februar 2025
Artikel online veröffentlicht:
15. April 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
Shannon Melissa Chan, Daniel Chan, Hon Chi Yip, Markus Wolfgang Scheppach, Ray Lam, Stephen KK Ng, Enders Kwok Wai Ng, Philip W Chiu. Artificial intelligence-assisted esophagogastroduodenoscopy improves procedure quality for endoscopists in early stages of training. Endosc Int Open 2025; 13: a25476645.
DOI: 10.1055/a-2547-6645
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References
- 1
Menon S,
Trudgill N.
How commonly is upper gastrointestinal cancer missed at endoscopy? A meta-analysis.
Endosc Int Open 2014; 2: E46-E50
MissingFormLabel
- 2
Hamashima C,
Fukao A.
Quality assurance manual of endoscopic screening for gastric cancer in Japanese communities.
Jpn J Clin Oncol 2016; 46: 1053-1061
MissingFormLabel
- 3
Bisschops R,
Areia M,
Coron E.
et al.
Performance measures for upper gastrointestinal endoscopy: A European Society of Gastrointestinal
Endoscopy quality improvement initiative. United European Gastroenterol J 2016; 4:
629-656
MissingFormLabel
- 4
Nagula S,
Parasa S,
Laine L.
et al.
AGA Clinical Practice Update on High-Quality Upper Endoscopy: Expert review. Clin
Gastroenterol Hepatol 2024; 22: 933-943
MissingFormLabel
- 5
Teh JL,
Tan JR,
Lau LJ.
et al.
Longer examination time improves detection of gastric cancer during diagnostic upper
gastrointestinal endoscopy. Clin Gastroenterol Hepatol 2015; 13: 480-487 e482
MissingFormLabel
- 6
Messmann H,
Bisschops R,
Antonelli G.
et al.
Expected value of artificial intelligence in gastrointestinal endoscopy: European
Society of Gastrointestinal Endoscopy (ESGE) Position Statement. Endoscopy 2022; 54:
1211-1231
MissingFormLabel
- 7
Yao K.
The endoscopic diagnosis of early gastric cancer. Ann Gastroenterol 2013; 26: 11-22
MissingFormLabel
- 8
Fernandez-Esparrach G,
Bernal J,
Lopez-Ceron M.
et al.
Exploring the clinical potential of an automatic colonic polyp detection method based
on the creation of energy maps. Endoscopy 2016; 48: 837-842
MissingFormLabel
- 9
Kanesaka T,
Lee TC,
Uedo N.
et al.
Computer-aided diagnosis for identifying and delineating early gastric cancers in
magnifying narrow-band imaging. Gastrointest Endosc 2018; 87: 1339-1344
MissingFormLabel
- 10
Misawa M,
Kudo SE,
Mori Y.
et al.
Artificial intelligence-assisted polyp detection for colonoscopy: Initial experience.
Gastroenterology 2018; 154: 2027-2029 e2023
MissingFormLabel
- 11
Urban G,
Tripathi P,
Alkayali T.
et al.
Deep learning localizes and identifies polyps in real time with 96% accuracy in screening
colonoscopy. Gastroenterology 2018; 155: 1069-1078 e1068
MissingFormLabel
- 12
Horie Y,
Yoshio T,
Aoyama K.
et al.
Diagnostic outcomes of esophageal cancer by artificial intelligence using convolutional
neural networks. Gastrointest Endosc 2019; 89: 25-32
MissingFormLabel
- 13
Ebigbo A,
Mendel R,
Ruckert T.
et al.
Endoscopic prediction of submucosal invasion in Barrett's cancer with the use of artificial
intelligence: a pilot study. Endoscopy 2021; 53: 878-883
MissingFormLabel
- 14
Wu L,
Zhang J,
Zhou W.
et al.
Randomised controlled trial of WISENSE, a real-time quality improving system for monitoring
blind spots during esophagogastroduodenoscopy. Gut 2019; 68: 2161-2169
MissingFormLabel
- 15
Siau K,
Beales ILP,
Haycock A.
et al.
JAG consensus statements for training and certification in oesophagogastroduodenoscopy.
Frontline Gastroenterol 2022; 13: 193-205
MissingFormLabel
- 16
Yao K,
Uedo N,
Kamada T.
et al.
Guidelines for endoscopic diagnosis of early gastric cancer. Dig Endosc 2020; 32:
663-698
MissingFormLabel
- 17
Beg S,
Ragunath K,
Wyman A.
et al.
Quality standards in upper gastrointestinal endoscopy: a position statement of the
British Society of Gastroenterology (BSG) and Association of Upper Gastrointestinal
Surgeons of Great Britain and Ireland (AUGIS). Gut 2017; 66: 1886-1899
MissingFormLabel
- 18
Park JM,
Kim SY,
Shin GY.
et al.
Implementation effect of institutional policy of EGD observation time on neoplasm
detection. Gastrointest Endosc 2021; 93: 1152-1159
MissingFormLabel
- 19
Hosokawa O,
Tsuda S,
Kidani E.
et al.
Diagnosis of gastric cancer up to three years after negative upper gastrointestinal
endoscopy. Endoscopy 1998; 30: 669-674
MissingFormLabel
- 20
Tatsuta M,
Iishi H,
Okuda S.
et al.
Prospective evaluation of diagnostic accuracy of gastrofiberscopic biopsy in diagnosis
of gastric cancer. Cancer 1989; 63: 1415-1420
MissingFormLabel
- 21
Pimenta-Melo AR,
Monteiro-Soares M,
Libanio D.
et al.
Missing rate for gastric cancer during upper gastrointestinal endoscopy: a systematic
review and meta-analysis. Eur J Gastroenterol Hepatol 2016; 28: 1041-1049
MissingFormLabel
- 22
Rodrigues T,
Keswani R.
Endoscopy training in the age of artificial intelligence: Deep learning or artificial
competence?. Clin Gastroenterol Hepatol 2023; 21: 8-10
MissingFormLabel
- 23
Grover SC,
Walsh CM.
Integrating artificial intelligence into endoscopy training: opportunities, challenges,
and strategies. Lancet Gastroenterol Hepatol 2024; 9: 11-13
MissingFormLabel