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Zeitschrift für Orthomolekulare Medizin 2025; 23(01): 22-29
DOI: 10.1055/a-2537-0484
Wissen

Magnesium: Der Schlüssel zur Langlebigkeit

Uwe Gröber
,
Klaus Kisters
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Zusammenfassung

Als pathogene Hauptfaktoren für Alterung und damit einhergehende Erkrankungen gelten oxidativer Stress mit Entzündungen und mitochondriale Dysfunktion. Die Hallmarks of Aging stehen unter dem Einfluss des endogenen Magnesiumstatus. Der Mineralstoff spielt eine wichtige Rolle in der Regulation von oxidativem Stress, Inflammation, Endothelfunktion, Telomerstruktur und mitochondrialer Funktion. Magnesiummangel beschleunigt die endotheliale und zelluläre Seneszenz. Bei der Supplementierung von Magnesium als Senolytikum ist Magnesiumtaurat zu bevorzugen.

Schlüsselwörter

Magnesium - Longevity - Hallmarks of Aging - Telomere - mitochondriale Dysfunktion - DNA - Epigenetik - Proteostase - zelluläre Seneszenz - Oxi-Inflammaging


Publikationsverlauf

Artikel online veröffentlicht:
22. April 2025

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