Planta Med 2025; 91(04): 173-188
DOI: 10.1055/a-2535-2003
Reviews

Green Tea Catechins: A Promising Anticancer Approach for Leukaemia

Authors

  • Łukasz Mazur

    1   Institute of Chemistry, University of Opole, Opole, Poland
  • Radosław Balwierz

    1   Institute of Chemistry, University of Opole, Opole, Poland
  • Krzysztof Michalak

    2   Institute of Medical Sciences, University of Opole, Opole, Poland
  • Wojciech Michalak

    2   Institute of Medical Sciences, University of Opole, Opole, Poland
  • Agata Jasińska-Balwierz

    3   Department of Pharmacology and Clinical Pharmacology, Academy of Silesia, Katowice, Poland
  • Mariia Shanaida

    4   Department of Pharmacognosy and Medical Botany, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine
  • Paweł Biernat

    5   Department of Drug Forms Technology, Faculty of Pharmacy, Wrocław Medical University, Wrocław, Poland
  • Tomasz Baj

    6   Department of Pharmacognosy with the Medicinal Plant Garden, Medical University of Lublin, Lublin, Poland
  • Izabela Jasicka-Misiak

    1   Institute of Chemistry, University of Opole, Opole, Poland

Abstract

Green tea catechins are bioactive polyphenolic compounds that possess a number of biological activities and potential health benefits. This review will focus on discussing the effects of green tea catechins, with a particular emphasis on clinical studies that evaluate their anticancer potential. Epigallocatechin gallate (EGCG), either as a stand-alone treatment or in conjunction with conventional anticancer therapies, represents a promising alternative strategy for the management of leukaemia. This review was based on a search of the scientific sources indexed in the databases PubMed and Scopus using the following keywords: ‘Camellia sinensis’, ‘tea catechins’, ‘anticancer’, ‘antioxidant’, ‘hematological cancer’, and ‘leukaemia’ in combination. A deeper comprehension of the multifaceted mechanisms and findings of research could facilitate the development of novel strategies and the integration of green tea catechins into clinical practice, thus enhancing treatment outcomes for patients with leukaemia.



Publication History

Received: 09 October 2024

Accepted: 27 January 2025

Article published online:
18 February 2025

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