Kurzfassung der KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease (Leitlinie für die klinische Praxis zur Diabetesbehandlung bei chronischer Nierenkrankheit): eine Aktualisierung auf Grundlage neuer Erkenntnisse

Zusammenfassung

Die Kidney Disease: Improving Global Outcomes (KDIGO) 2022 Klinische Praxisrichtlinie für die Behandlung des Diabetes bei chronischer Nierenkrankheit (chronic kidney disease, CKD) stellt eine Aktualisierung der KDIGO-Leitlinie 2020 dar. Die Leitlinie richtet sich an eine breite Zielgruppe von Klinikern, die Menschen mit Diabetes und CKD behandeln. Zu den Themenbereichen, deren Empfehlungen auf der Grundlage neuer Erkenntnisse aktualisiert wurden, gehören die Kapitel 1: Umfassende Versorgung von Patienten mit Diabetes und CKD sowie Kapitel 4: Glukosesenkende Therapien bei Patienten mit Typ-2-Diabetes (T2 D) und CKD. Der Inhalt früherer Kapitel zur glykämischen Überwachung und zu den Zielen bei Patienten mit Diabetes und CKD (Kapitel 2), Lebensstilinterventionen bei Patienten mit Diabetes und CKD (Kapitel 3) und Ansätzen für das Management von Patienten mit Diabetes und CKD (Kapitel 5) werden als aktuell erachtet und wurden nicht geändert. Diese aktualisierte Leitlinie wurde nach einem eindeutigen Prozess der Evidenzprüfung und -bewertung entwickelt. Die Behandlungsansätze und Leitlinienempfehlungen basieren auf systematischen Übersichten relevanter Studien und Bewertung der Evidenz-Qualität. Die Stärke der Empfehlungen folgt dem GRADE-Ansatz (Grading of Recommendations Assessment, Development and Evaluation).

Die Grenzen der Evidenzen werden erörtert, und es werden Bereiche identifiziert, in denen zusätzliche Forschung erforderlich ist.

Abstract

The Kidney Disease: Improving Global Outcomes (KDIGO) 2022 Clinical Practice Guideline for the Management of Diabetes in Chronic Kidney Disease (CKD) is an update of the KDIGO 2020 guideline. The guideline is aimed at a broad audience of clinicians treating people with diabetes and CKD. Topics with recommendations updated based on new evidence include Chapter 1: Comprehensive Care in Patients with Diabetes and CKD, and Chapter 4: Glucose-Lowering Therapies in Patients with Type 2 Diabetes (T2 D) and CKD. The content of previous chapters on glycemic monitoring and targets in patients with diabetes and CKD (Chapter 2), lifestyle interventions in patients with diabetes and CKD (Chapter 3), and approaches to the management of patients with diabetes and CKD (Chapter 5) are considered current and have not been changed. This updated guideline was developed through a rigorous process of evidence review and evaluation. Treatment approaches and guideline recommendations are based on systematic reviews of relevant studies and assessment of evidence quality. The strength of the recommendations follows the GRADE approach (Grading of Recommendations Assessment, Development and Evaluation). The limitations of the evidence are discussed, and areas where additional research is needed are identified.

Schlüsselwörter

Angiotensin-Converting-Enzym-Inhibitor - Angiotensin-II-Rezeptor-Blocker - chronische Nierenkrankheit - Dialyse - Evidenzbasiert - GLP-1-Rezeptor-Agonist - Glykämie - glykämische Überwachung - glykämische Ziele - Leitlinie - HbA1c - Hämodialyse - KDIGO - Lebensstil - Metformin - Mineralokortikoid-Rezeptor-Antagonist - Versorgungsmodelle - Ernährung - Renin-Angiotensin-System - Selbstmanagement - SGLT2-Hemmer - systematische Überprüfung - teambasierte Versorgung

Keywords

Angiotensin-converting enzyme inhibitor - Angiotensin II receptor blocker - chronic kidney disease - dialysis - evidence-based - GLP-1 receptor agonist - Glycemia - glycemic monitoring - glycemic targets - guideline - HbA1c (hemoglobin A1c) - hemodialysis - KDIGO (Kidney Disease: Improving Global Outcomes) - lifestyle - metformin - mineralocorticoid receptor antagonist - care models - nutrition - renin-angiotensin system - self-management - SGLT2 inhibitor - systematic review - team-based care

^* Zahlungen an die Institution.

Publication History

Article published online:
27 January 2025

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